icono-certificado-011

Studies

Tests and Studies developed in Elaboration National and International Laboratories

ALLERGISA clinical trial reports

Soportandolos siguientes claims:

1. Approved by Dentists: supported by safety evaluation and dental evaluation.

2. Clinically proven: supported by dental safety evaluation.

3. Sensation of cleanliness and against bad breath: supported by dental clinical evaluation and self-perceived efficacy evaluation.

4. Anti-inflammatory and anti-hemorrhagic property: supported by dental clinical evaluation and evaluation of self-perceived efficacy.

Final Dosage Reports

Evaluation of the antimicrobial efficacy of the Kirus mouthwash is carried out with the Time Kill Test, which evaluates the antimicrobial activity, demonstrating the quantitative reduction of the microbial population as a function of contact time.

Microorganism: Aggregatibacter Actinomycetemcomitans ATCC 29522 Reduction greater than 99.99% (4 log) of the initial microbial population from 1 minute of contact for the microorganism Aggregatibacter Actinomycetemcomitans.
Microorganism: Candida albicans ATCC 10231 Maximum reduction of 76.1% (0.62 log) of the initial microbial population in 2 minutes of contact for the microorganism Candida albicans.
Microorganism: Candida albicans ATCC 10231 Reduction greater than 99% (2 log) of the initial microbial population from 1 minute of contact for the microorganism Fusobacterium nucleatum.

Mouthwash stability study

It is concluded that the new product Kirus Mouthwash, 300ml bottle presentation is stable according to the stability parameters equivalent to three years under normal USP, FDA, ICH, WHO shelf conditions for stability study.

KIRUS mouthwash technical sheet

Product made through a controlled process that is important for obtaining top quality products, complying with Good Manufacturing Practices at all stages of the process.